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Isaac_Asimov

Science and Art

“There is an art to science, and science in art; the two are not enemies, but different aspects of the whole.”
  • Source: Isaac Asimov, chapter epigraph in Isaac Asimov’s Book of Science and Nature Quotations, edited by Isaac Asimov and Jason A. Shulman, published in 1988 by Weidenfeld and Nicolson, New York. Chapter 65, page 251. ISBN 1-555-84111-2.

Claude_Bernard

Alter Theory Not Nature

“The theories which embody our scientific ideas as a whole are, of course, indispensable as representations of science. They should also serve as a basis for new ideas. But as these theories and ideas are by no means immutable truth, one must always be ready to abandon them, to alter them or to exchange them as soon as they cease to represent the truth. In a word, we must alter theory to adapt it to nature, but not nature to adapt it to theory.”
  • Source: From the book "An Introduction to the Study of Experimental Medicine" written by Claude Bernard published in French in 1865 as "Introduction à l'étude de la médecine expérimentale". Translated to English by Henry Copley Greene in 1927 and republished by Henry Shuman, Inc. in 1949. Chapter II, page 39. Available online at https://archive.org/details/b21270557 retrieved 2024.

Bible_Verses

Tower Of Babel (Genesis 11:4-6)

(4) “And they said, Go to, let us build us a city and a tower, whose top may reach unto heaven; and let us make us a name, lest we be scattered abroad upon the face of the whole earth.”
(5) “And the LORD came down to see the city and the tower, which the children of men builded.”
(6) “And the LORD said, Behold, the people is one, and they have all one language; and this they begin to do: and now nothing will be restrained from them, which they have imagined to do.”

Nicolaus_Copernicus

Motion of the Earth

“Hence, I feel no shame in asserting that this whole region engirdled by the moon, and the center of the earth, traverse this grand circle amid the rest of the planets in an annual revolution around the sun. Near the sun is the center of the universe. Moreover, since the sun remains stationary, whatever appears as a motion of the sun is really due rather to the motion of the earth.”
  • Source: Book 1, Ch. 10 - De revolutionibus orbium coelestium (1543)

David_Deutsch

Gigantic Computation

“Think of all our knowledge-generating processes, our whole culture and civilization, and all the thought processes in the minds of every individual, and indeed the entire evolving biosphere as well, as being a gigantic computation. The whole thing is executing a self-motivated, self-generating computer program. More specifically it is, as I have mentioned, a virtual-reality program in the process of rendering, with ever-increasing accuracy, the whole of existence.”

David_Kipping

Parent Reality Different

“If we concede that the possibility that our observations and understanding of physics may in fact be simulated... our knowledge of physics is wholly local to the simulation and may have no real bearing on the constraints that affect a parent reality, whose rules and limitations may be entirely different.”
  • Source: David Kipping from the paper “A Bayesian Approach to the Simulation Argument”, published 2020 in the journal ‘Universe’, volume 6, issue 8. DOI:10.3390/universe6080109. Online at https://www.mdpi.com/2218-1997/6/8/109 (2025).

Steven_Pinker

Neurons to Consciousness

“None of us has a brain that can actually put us in touch with reality unaided with truth. I've just shown you a bunch of gadgetry that responds to things that are essential to our survival, things that prevent us from falling off cliffs and bumping into trees. But they don't actually correspond to any clear description of the world as it is. So we have, for example, circuitry that responds to the edges rather than the physical distribution of light, because edges are important, that's where objects leave off and their backgrounds begin. Moreover, they can be fooled, as I did with each one of you. That since our neural circuitry does consist of a mechanism, not a pipeline to the truth or a window onto objective reality. That is naïve realism we know is false because there are illusions. You can't just trust your senses. That means we need some way of augmenting the faculties that nature gave us to make our beliefs as accurate as possible. Which of course is why the early modern philosophers made such a big deal of visual illusions. They said you can't just open your eyes and see the world as it is. Look at all these illusions. So what we do, what gives some of us confidence that our beliefs are objectively true is that they are part of an institutional infrastructure of testing and criticism and logic and determining which hypotheses withstand criticism and attempts at refutation. Devising exotic arrangements of reality to reflect the way reality is put together, namely experiments. Thanks to this huge network of minds, each one of them making up for deficits of all the others, we like to think that we have a collective grasp on truth that none of us individually can have. But of course, it's always fallible. The religious beliefs I think were actually pretty reasonable hypotheses in earlier states of our collective knowledge. Even Richard Dawkins said that before Darwin he probably would have been a creationist because the cosmic engineer was the only available explanation for the obvious adaptive complexity of living things. I would add that prior to the advent of modern neuroscience I probably would have believed in souls because there was no better explanation for phenomena such as that people respond intelligently to their environments. When you dream some part of you is up and about the world while your body is in bed the whole time. That seems like there must be some part of you that can leave your body. When a person suddenly dies some kind of animating force no longer seems to be animating the body that was there just a few minutes ago. So the soul hypothesis is not a stupid or irrational belief, nor is creationism if it's the best that you have. Now, of course, we can do better. But doing better in part depends not just on this cumulative weight of evidence and argument. But because few of us can actually reconstruct the scientific observations that justify the theory of natural selection or the theory of neural networks, all of us, at least a little bit, take it on faith in the following sense; that there is a community that you trust enough because when they have been challenged to defend their beliefs they can connect them to reality. They have shown that it isn't magic. That they have given reason to trust them because they've convinced you that they're the mores of their culture, of their scientific culture, designed so that they will find true things and weed out false things. If you don't have a degree of solidarity or trust, if you think that scientists are all in cahoots with big corporations or are trying to tear down all faith and values and meaning and you simply refuse to follow through the very long chain of deduction that connects the claims to the experiments, then you'll naturally reject it just because it's not your tribe. For you and me scientists are our tribe and we're apt to give them some credibility, indeed some credulousness, knowing that if ever challenged it would be repaid. But unless you trace that through it can be all too easy to reject the conclusions of science, and indeed a number of studies have shown that contrary to the common belief that people believe in falsehoods, such as that vaccines cause autism or that humans were created five thousand years ago or that the burning of fossil fuels has no effect on global temperatures, it turns out that people with those beliefs that we have every reason to believe are false are no more scientifically naïve on average than people that have beliefs that are scientifically justified. You give a test on evolution to a bunch of people who believe in evolution, give it to a bunch of creationists, there's not much difference in how well they score. In fact, often they are equal. Likewise, the typical grasp of climate science among someone who signs on to the scientific consensus is not much better than the adamant deniers. That kind of dashes the hope that simply by increasing the quality of science education you will lead people to more accurate beliefs. There, in addition, has to be a dissociation of who you think are the good guys and who are the bad guys from who has the best claims to truth. That's what it depends on.”

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Adam_Smith

Three Great Orders

“The whole annual produce of the land and labour of every country... naturally divides itself, it has already been observed, into three parts; the rent of land, the wages of labour, and the profits of stock; and constitutes a revenue to three different orders of people; to those who live by rent, to those who live by wages, and to those who live by profit. These are the three great, original, and constituent orders of every civilised society... The interest of the first of those three great orders, it appears from what has been just now said, is strictly and inseparably connected with the general interest of the society. Whatever either promotes or obstructs the one, necessarily promotes or obstructs the other... The interest of the second order, that of those who live by wages, is as strictly connected with the interest of the society as that of the first... Employers constitute the third order, that of those who live by profit. It is the stock that is employed for the sake of profit which puts into motion the greater part of the useful labour of every society... But the rate of profit does not, like rent and wages, rise with the prosperity and fall with the declension of the society. On the contrary... The interest of this third order, therefore, has not the same connection with the general interest of the society as that of the other two... The interest of the dealers... is always in some respects different from, and even opposite to, that of the public. To widen the market and to narrow the competition... The proposal of any new law or regulation of commerce which comes from this order ought always to be listened to with great precaution, and ought never to be adopted till after having been long and carefully examined, not only with the most scrupulous, but with the most suspicious attention. It comes from an order of men whose interest is never exactly the same with that of the public, who have generally an interest to deceive and even to oppress the public, and who accordingly have, upon many occasions, both deceived and oppressed it.”
  • Source: Adam Smith (1776) An Inquiry into the Nature and Causes of the Wealth of Nations. London, England: ‎W. Strahan and T. Cadell. Book I chapter XI.

John_Steinbeck

Great Difficulty with Good Hypothesis

“There is one great difficulty with a good hypothesis. When it is completed and rounded, the corners smooth and the content cohesive and coherent, it is likely to become a thing in itself, a work of art. It is then like a finished sonnet or a painting completed. One hates to disturb it. Even if subsequent information should shoot a hole in it, one hates to tear it down because it once was beautiful and whole. One of our leading scientists, having reasoned a reef in the Pacific, was unable for a long time to reconcile the lack of a reef, indicated by soundings, with the reef his mind told him was there.”
  • Source: John Steinbeck, In John Steinbeck and Edward Flanders Ricketts Sea of Cortez: a Leisurely Journal of Travel and Research (1941), 179-80.

Mark_Twain

Annihilation

“Annihilation has no terrors for me, I have already tried it before I was born — a hundred million years — and I have suffered more in an hour, in this life, than I remember to have suffered in the whole hundred million years put together.”
  • Source: Mark Twain (Samuel Clemens) in his autobiography, dictated circa 1907 published 1924 in ‘Mark Twain’s Autobiography’ by Mark Twain, Volume 1 and 2, edited by Albert Bigelow Paine, Harper & Brothers, New York.

Matt_Warner

Surprising Change

“It's surprising how a little affair sometimes will change a man's whole life.”
  • Source: Matt Warner in the book “Last of the Bandit Riders” Originally published in 1940, republished in 2000 by Big Mood Traders, ISBN 0-9656694-1-6. Chapter 1.

Stephen_Wolfram

Computational Irreducibility

“I’ve increasingly come to view the whole fundamental story of science as being about the interplay between computational irreducibility and computational reducibility. The computational nature of things inevitably leads to computational irreducibility. But there are slices of computational reducibility that inevitably exist on top of this irreducibility that are what make it possible for us — as computationally bounded entities — to identify meaningful scientific laws and to do science.”